Autor: |
Vinoth Krishnan, Venkatachalam Ananth, Jayasudha Velayutham, Pandiaraj Manickam, Murugan Veerapandian |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Biosensors, Vol 13, Iss 1, p 6 (2022) |
Druh dokumentu: |
article |
ISSN: |
2079-6374 |
DOI: |
10.3390/bios13010006 |
Popis: |
With the ever-growing global wound care market, demand for robust redox-active healthcare material is obvious for the construction of wearable sensor platforms. Surface reactive functional group-rich material like chitosan holds huge potential for electrochemical biosensor application. Herein, a metal-free redox-active chitosan–butein (CSB) bioconjugate is processed into epidermal bioadhesive electrode material useful for pH sensors promising toward wound site analysis. A two-electrode system devised for conducting carbon-reinforced silver chloride paste and CSB-modified carbon/silver chloride matrix was used as a reference and working electrodes, respectively. Dimensions of working and reference electrodes (4 mm) were designed by 2D cutter plotter-assisted stenciling. The cross-sectional topology of the constructed adhesive CSB-sensor platform exhibits an average surface thickness of 183 ± 2 μm. Cyclic voltammetric analysis revealed the inherent 2e−/2H+ transfer attributed to the catechol OH groups of graft polymerized CSB modified on adhesive gauze. As-fabricated modified electrode substrates exhibit distinguishable potential differences with respect to electrolytes of varied pH (between 5 to 9), promising for wound site analysis. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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