| Autor: |
Mahamat Abakar Ali, Nyemb Jean Noël, Gade Isaac Silvère, Ngenge Alfred Tamfu, Talla Emmanuel, Céline Henoumont, Sophie Laurent, Mbafor Joseph Tanyi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Open Chemistry, Vol 18, Iss 1, Pp 239-243 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2391-5420 |
| DOI: |
10.1515/chem-2020-0016 |
| Popis: |
The aim of this work was to evaluate in vitro antiradical scavenging activity of propolis from Nkambe (North-West, Cameroon). The polyphenol content of the acetone extract was evaluated using the Folin-Ciocalteu reagent as 0.166±0.008 gGAE/100 gRM. Antiradical scavenging activity of hexane and acetone extracts was carried out on DPPH using ascorbic acid as standard. The results showed that the extracts possess antiradical activity with IC50 of 141 μg/mL and 267 μg/mL for acetone and hexane extracts, respectively. The column chromatography separation on silica gel of the hexane fractionyielded compounds 1 to 3. The structures of these compounds were elucidated by NMR and mass spectrometry data as Lupenone (1), a mixture of α and ß-Amyrin (2) and lastly Hexatriacontanoic acid (3) which was described for the first time from propolis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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