| Autor: |
James J. Young, Joshua S. Friedman, Thomas J. Oxley, Christina Palmese, Fedor Panov, Saadi Ghatan, Johanna T. Fifi, Lara V. Marcuse |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Epilepsy and Behavior Case Reports, Vol 10, Iss , Pp 25-28 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2213-3232 |
| DOI: |
10.1016/j.ebcr.2018.04.003 |
| Popis: |
The mechanism of amobarbital action during the intracarotid amobarbital procedure is poorly understood. We report a patient case who underwent IAP while implanted with bilateral stereo-EEG. We analyzed the spectral power, phase amplitude coupling, and cluster-phase group synchrony during the procedure. Delta and gamma power increased bilaterally. By contrast, phase amplitude coupling increased only ipsilateral to the injection. Similarly, 4–30 Hz cluster-phase group synchrony declines and gamma cluster-phase group synchrony increases only ipsilateral to the injection. These results suggest that a possible additional mechanism for amobarbital action in the IAP is by altering the precise timing of oscillatory activity. Keywords: Intracarotid amobarbital procedure, Wada, Stereo-EEG, Synchrony, Phase amplitude coupling, Epilepsy surgery |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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