Development of voltammetric melanin sensor with 2,5-dimethylfuran modified platinum electrode
| Autor: | Muammer Burç, Dilek Asma, Serap Titretir Duran |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Macedonian Journal of Chemistry and Chemical Engineering, Vol 40, Iss 2 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1857-5552 1857-5625 |
| DOI: | 10.20450/mjcce.2021.2399 |
| Popis: | In this study, an electrochemical sensor was developed for the electrochemical determination of melanin. For this purpose, phosphate buffer salt (PBS, pH 7.00) solution was used as an electrolyte, 2,5-dimethylfuran (2,5-DMF) as a monomer, Pt wire as the auxilary electrode, Ag/AgCl electrode as the reference electrode and a platinum electrode as the working electrode. The modification of the electrode was performed by polymerization of 2,5-DMF at the bare Pt electrode surface using the cyclic voltammetry method. Parameters such as film thickness, scan rate and pulse amplitude with prepared 2,5-DMF modified platinum electrode (p(2,5-DMF)/PtE) were optimized by square wave voltammetry (SWV) in PBS buffer containing melanin. In optimum conditions, the anodic peak height showed a linear increase with the melanin concentration. The limit of detection (LOD) and limit of quantitation (LOQ) were calculated to be 0.088 mmol/l and 0.292 mmol/l, respectively, with melanin concentrations ranging from 0.10 to 2.20 mmol/l and the correlation coefficient (R2) was calculated as 0.9985. Stability of the prepared sensor was found to be 99.63% by using the reproducibility experiments (n = 15). |
| Databáze: | Directory of Open Access Journals |
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