Technical and clinical considerations for electroencephalography-based biomarkers for major depressive disorder

Autor: Leif Simmatis, Emma E. Russo, Joseph Geraci, Irene E. Harmsen, Nardin Samuel
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: npj Mental Health Research, Vol 2, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 2731-4251
DOI: 10.1038/s44184-023-00038-7
Popis: Abstract Major depressive disorder (MDD) is a prevalent and debilitating psychiatric disease that leads to substantial loss of quality of life. There has been little progress in developing new MDD therapeutics due to a poor understanding of disease heterogeneity and individuals’ responses to treatments. Electroencephalography (EEG) is poised to improve this, owing to the ease of large-scale data collection and the advancement of computational methods to address artifacts. This review summarizes the viability of EEG for developing brain-based biomarkers in MDD. We examine the properties of well-established EEG preprocessing pipelines and consider factors leading to the discovery of sensitive and reliable biomarkers.
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