Herpes simplex virus 1 rhombencephalitis in a patient with chromosomally integrated human herpesvirus-6A

Autor: Raquel Silva, Vitor Duque, Rita Magano, Luís Trindade
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: IDCases, Vol 22, Iss , Pp e00983- (2020)
Druh dokumentu: article
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2020.e00983
Popis: Central nervous system infection caused by Herpes simplex virus 1 remains a significant cause of morbidity and mortality in transplant patients. Additionally, the clinical implications of the recently discovered Human herpesvirus 6A are still under investigation.Hereby, we report a clinical case of an immunosuppressed patient following kidney transplantation and with chromosomally integrated human herpesvirus-6A (CIHHV-6A) that developed rhombencephalitis due to herpes virus simplex 1.This case highlights the importance of investigating the CIHHV-6 status in the differential diagnosis whenever a human herpesvirus is detected in the cerebrospinal fluid.
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