Predictive factors for early response to methimazole in children and adolescents with Graves disease: a single-institute study between 1993 and 2013

Autor: Sun Mi Hwang, Min Sun Kim, Dae-Yeol Lee
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Annals of Pediatric Endocrinology & Metabolism, Vol 21, Iss 2, Pp 70-74 (2016)
Druh dokumentu: article
ISSN: 2287-1012
2287-1292
DOI: 10.6065/apem.2016.21.2.70
Popis: PurposeWe aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD).MethodsOur study included 44 pediatric patients who were diagnosed with GD between January 1, 1993, and December 31, 2013, and were available for follow-up, achieving a normalization of thyroid functions (TFs) at the Chonbuk National University Hospital Pediatric Department. We retrospectively analyzed TFs such as tri-iodothyronine (T3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), and thyroid antibody levels at diagnosis. We also examined their family history of thyroid disease, symptoms at presentation, and normalization time for TF after treatment. We divided our clinical series of patients into the following 4 age groups:
Databáze: Directory of Open Access Journals