Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning
| Autor: | Ali Banagozar Mohammadi, Hamid Noshad, Ali Ostadi, Ali Reza Ghaffari, Maryam Zaare Nahandi, Ahad Banagozar Mohammadi |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Iranian Journal of Toxicology, Vol 9, Iss 28, Pp 1284-1286 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2008-2967 2251-9459 |
| Popis: | Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency of contact. Management of these patients consists of conservative and palliative therapies to reduce the oxidative effects. Case: The case was a 29-year-old girl with a Master of Sciences degree in genetics who worked in a university research center with previous history of depression. She had ingested 100cc of 30% Acrylamide solution for intentional suicide attempt. The patient was successfully managed using N-acetyl cysteine, vitamin C, and melatonin. Conclusion: Early diagnosis and appropriate treatment with recommended agents together with supportive therapies can save the life of patients exposed to potentially lethal doses of acrylamide, although intentional or accidental. |
| Databáze: | Directory of Open Access Journals |
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