Increased red blood cell distribution width associates with cancer stage and prognosis in patients with lung cancer.

Autor: Yasuko Koma, Akira Onishi, Hirofumi Matsuoka, Nao Oda, Naoya Yokota, Yusuke Matsumoto, Midori Koyama, Nobuhiko Okada, Nariyasu Nakashima, Daiki Masuya, Harukazu Yoshimatsu, Yujiro Suzuki
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 11, p e80240 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0080240
Popis: BACKGROUND: Red cell distribution width (RDW), one of many routinely examined parameters, shows the heterogeneity in erythrocyte size. We investigated the association of RDW levels with clinical parameters and prognosis of lung cancer patients. METHODS: Clinical and laboratory data from 332 patients with lung cancer in a single institution were retrospectively studied by univariate analysis. Kaplan-Meier survival analysis and Cox proportional hazard models were used to examine the effect of RDW on survival. RESULTS: THE RDW LEVELS WERE DIVIDED INTO TWO GROUPS: high RDW (>=15%), n=73 vs. low RDW, n=259 (
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