Cardiovascular outcomes in patients with intraventricular conduction blocks: A sixteen-year follow-up in a state-wide database

Autor: John S. Pantazopoulos, MD, Alice David, MS, PhD, William J. Kostis, PhD, MD, Nora M. Cosgrove, RN, John B. Kostis, MD
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Hellenic Journal of Cardiology, Vol 58, Iss 3, Pp 194-201 (2017)
Druh dokumentu: article
ISSN: 1109-9666
DOI: 10.1016/j.hjc.2016.11.034
Popis: Background: To assess the adverse clinical effects of left anterior hemiblock alone or in combination with right bundle branch block and of complete left bundle branch block in comparison with isolated right bundle branch block and the relationship of these effects with altered mechanoelectric factors resulting in left ventricular dysfunction. Methods: In a 16-year follow-up study using a statewide database, we studied the occurrence of mortal and morbid cardiovascular (CV) events among patients without apparent ischemic heart disease who had left anterior hemiblock (LAHB, n=4273, right bundle branch block (RBBB) with LAHB (BFBB, n=1857) and left bundle branch block (LBBB, n=9484 compared to isolated RBBB (n=25288). Results: After adjustment for demographics, co-morbidities and insurance, LAHB was associated with a significant excess risk of all-cause death (HR 1.134, 95% CI 1.061-1.213, p=0.0002) and CV death (HR 1.329, 95% CI 1.174-1.501, p
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