State of antioxidant blood system at physiological pregnancy and pregnancy complicated with bleeding

Autor: Z. I. Mikashinowich, Ye. V. Olempieva
Jazyk: English<br />Russian
Rok vydání: 2008
Předmět:
Zdroj: Бюллетень сибирской медицины, Vol 7, Iss 2, Pp 101-105 (2008)
Druh dokumentu: article
ISSN: 1682-0363
1819-3684
DOI: 10.20538/1682-0363-2008-2-101-105
Popis: The task of our investigation was the analysis of enzyme activity of antioxidant defense in women blood at physiological pregnancy and pregnancy complicated with hypertension. It was established that hyper production of hydrogen peroxide and glutathione peroxidase activation at physiological pregnancy improved microcirculation due to vasodilatation effect of hydrogen peroxide. It was established that activation of superoxiddysmutase and myeloperoxidase at pregnancy complicated with hypertension developed endothelial dysfunction owing to citotoxic effects of hydrogen peroxide.
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