Overview of Pancreatic Cancer Epidemiology in Europe and Recommendations for Screening in High-Risk Populations

Autor: Olga Partyka, Monika Pajewska, Daria Kwaśniewska, Aleksandra Czerw, Andrzej Deptała, Michał Budzik, Elżbieta Cipora, Izabela Gąska, Lucyna Gazdowicz, Aneta Mielnik, Katarzyna Sygit, Marian Sygit, Edyta Krzych-Fałta, Daria Schneider-Matyka, Szymon Grochans, Anna M. Cybulska, Jarosław Drobnik, Ewa Bandurska, Weronika Ciećko, Piotr Ratajczak, Karolina Kamecka, Michał Marczak, Remigiusz Kozłowski
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancers, Vol 15, Iss 14, p 3634 (2023)
Druh dokumentu: article
ISSN: 2072-6694
DOI: 10.3390/cancers15143634
Popis: Pancreatic cancer is the seventh most common cause of death in the group of oncological diseases. Due to the asymptomatic course, early diagnosis is difficult. Currently, early detection methods are only used in high-risk groups. A literature review based on the available results of observational studies on patients with pancreatic cancer and people from high-risk groups was used to summarize the knowledge on risk factors. The GLOBOCAN 2020 data were used to assess the epidemiological situation in Europe. A summary of screening recommendations was prepared based on the available documents from medical organizations and associations. Pancreatic cancer risk factors are divided into two main groups: non-modifiable factors, e.g., hereditary factors and age, which increase the risk of developing this disease, and modifiable factors—BMI, smoking, and alcohol consumption. Hereditary factors account for 10% of pancreatic cancer cases. The highly specialized methods of early detection, (MRI, CT, or EUS) are used for screening high-risk populations. Of all the imaging methods, EUS is considered the most sensitive for pancreatic cancer and allows an accurate assessment of the size of even small lesions (
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje