Cognitive function assessed by Mini-mental state examination and risk of all-cause mortality: a community-based prospective cohort study

Autor: Yongkang Su, Jing Dong, Jin Sun, Yan Zhang, Shouyuan Ma, Man Li, Anhang Zhang, Bokai Cheng, Shuang Cai, Qiligeer Bao, Shuxia Wang, Ping Zhu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Geriatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 1471-2318
DOI: 10.1186/s12877-021-02471-9
Popis: Abstract Background The Mini-Mental State Examination (MMSE) is the most widely used instrument to test cognitive functioning. The present study prospectively investigated the association between MMSE scores, MMSE domains, and all-cause mortality. Methods A total of 2134 participants aged 60 years or over, selected from one urban community-dwelling population in China, were enrolled in the study. The cognitive test was performed by use of the MMSE at baseline, and covariates were recorded simultaneously. Cox regression models were used for examining the cognitive function, expressed by different MMSE transformations, and all-cause mortality. After followed up for a median of 10.8 years (ranging from 1.0 to 11.3 years), loss to follow-up was 13.1% and 1854 individuals were finally included in the analyses. Results The subjects had the mean (SD) age of 71.01 (7.00) years, and 754 (40.67%) of them were women. Per point increase on MMSE scores was associated a 4% decreased risk of all-cause mortality [hazard ratio (HR): 0.96; 95%confidence interval (CI): 0.93–0.98]; compared to MMSE scores of ≥24, MMSE scores of
Databáze: Directory of Open Access Journals