Post-stroke depression: predictors and prophylaxis

Autor: T. M. Muratova, D. M. Khramtsov, O. M. Stoyanov, Yu. M. Vorokhta, M. S. Vikarenko, G. G. Kozlova
Jazyk: English<br />Spanish; Castilian<br />Polish<br />Russian<br />Ukrainian
Rok vydání: 2019
Předmět:
Zdroj: Journal of Education, Health and Sport, Vol 9, Iss 1, Pp 452-462 (2019)
Druh dokumentu: article
ISSN: 2391-8306
DOI: 10.5281/zenodo.3235546
Popis: The purpose of the study was to evaluate the effectiveness of prevention of post-stroke depression in patients with acute cerebrovascular accident It was shown that the incidence of PID in patients with ischemic stroke exceeds 30%. In assessing the role of various risk factors among the examined patients with PID, the prevalence of male patients (OR = 1.3 (1.1-1.5)), under the age of 55 (1.7 (1.3-1.9 )), with indications in the history of episodes of depression in the past (1.6 (1.4-1.8)), as well as alcohol abuse (1.2 (1.0-1.3)). In 31 (58.5%) there was a localization of focal ischemia in the frontal lobe of the dominant hemisphere. The use of both SIRS and an antidepressant with multimodal effect - vortioxetine was sufficiently effective in PID, but vortioxetin showing the best results - from 8,80,1 points to 6,20,1 points. The paper considers the expediency of the use of vorothoxetine in order to prevent PID in patients with ischemic stroke.
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