| Autor: |
Eric Lowet, Krishnakanth Kondabolu, Samuel Zhou, Rebecca A. Mount, Yangyang Wang, Cara R. Ravasio, Xue Han |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-022-35314-1 |
| Popis: |
The neurophysiological mechanisms of deep brain stimulation remain poorly understood. Through fluorescence voltage imaging of individual hippocampal neurons in awake mice, the authors show that deep brain stimulation causes membrane depolarization that impairs a neuron’s ability to respond to intrinsic network activity patterns and optogenetic somatic depolarization, thereby creating an informational lesion. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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