Comparative analysis of transcriptional profiles of Schistosoma japonicum adult worms derived from primary-infected and re-infected water buffaloes

Autor:	Yudan Mao, Chuanchuan He, Hao Li, Ke Lu, Zhiqiang Fu, Yang Hong, Yamei Jin, Jiaojiao Lin, Xin Zhang, Jinming Liu
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Comparative analysis Primary-infected Re-infected RNA-Seq Schistosoma japonicum Water buffalo Infectious and parasitic diseases RC109-216
Zdroj:	Parasites & Vectors, Vol 12, Iss 1, Pp 1-16 (2019)
Druh dokumentu:	article
ISSN:	1756-3305
DOI:	10.1186/s13071-019-3600-y
Popis:	Abstract Background Schistosoma japonicum (S. japonicum) is an important zoonotic parasite that is prevalent in China and parts of Southeast Asia. Water buffaloes are an important reservoir and the main transmission sources of S. japonicum. However, self-curing and resistance to re-infection have been observed in water buffaloes. Results In this study, we compared the morphometry and differences in transcriptional expression of adult S. japonicum worms recovered from primary-infected and re-infected water buffaloes using Illumina RNA-sequencing (RNA-Seq) technology. Results of morphometry analysis revealed that adult S. japonicum worms recovered from re-infected water buffaloes were runtish with smaller organs. The ventral length of male worms was shorter in re-infected buffaloes (328 ± 13 vs 273 ± 8 µm, P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/67e9443a7c3641d197e7f3b1bb94d512 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.