SODIUM POLYPRENYL PHOSPHATE (PHOSPRENYL) EXERTS AN IL-2-DEPENDENT RESTORATIVE EFFECT UPON IN VIVO DTH INHIBITION

Autor:	S. M. Sobolev, T. N. Nikolaeva, E. A. Grigorieva, A. V. Pronin
Jazyk:	ruština
Rok vydání:	2014
Předmět:	γ-globulin interleukin-2 polyprenols dth listeriosis Immunologic diseases. Allergy RC581-607
Zdroj:	Медицинская иммунология, Vol 14, Iss 4-5, Pp 399-402 (2014)
Druh dokumentu:	article
ISSN:	1563-0625 2313-741X
DOI:	10.15789/1563-0625-2012-4-5-399-402
Popis:	Abstract. We have shown that polyprenyl phosphate (phosprenyl) competes with interleukin 2 for binding with serum γ-globulin. It was also demonstrated that phosprenyl restores delayed type hypersensitivity induced by Listeria monocytogenes, after its inhibition with a γ-globulin which binds to IL-2 and blocks its activity. A role of serum γ-globulin and Phosprenyl in regulation of IL-2-dependent processes is discussed.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a67cad233db4442185b9784f6b3022fd Zobrazit plný text záznamu View record in DOAJ