Aneurysm Rupture Prediction Based on Strain Energy-CFD Modelling

Autor: Ahmed M. Al-Jumaily, Abd Halim Bin Embong, Mohammad AL-Rawi, Giri Mahadevan, Shukei Sugita
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Bioengineering, Vol 10, Iss 10, p 1231 (2023)
Druh dokumentu: article
ISSN: 2306-5354
DOI: 10.3390/bioengineering10101231
Popis: This paper presents a Patient-Specific Aneurysm Model (PSAM) analyzed using Computational Fluid Dynamics (CFD). The PSAM combines the energy strain function and stress–strain relationship of the dilated vessel wall to predict the rupture of aneurysms. This predictive model is developed by analyzing ultrasound images acquired with a 6–9 MHz Doppler transducer, which provides real-time data on the arterial deformations. The patient-specific cyclic loading on the PSAM is extrapolated from the strain energy function developed using historical stress–strain relationships. Multivariant factors are proposed to locate points of arterial weakening that precede rupture. Biaxial tensile tests are used to calculate the material properties of the artery wall, enabling the observation of the time-dependent material response in wall rupture formation. In this way, correlations between the wall deformation and tissue failure mode can predict the aneurysm’s propensity to rupture. This method can be embedded within the ultrasound measures used to diagnose potential AAA ruptures.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje