Evaluation of platelet indices and count in patients with ischemic heart disease compared to normal population
| Autor: | SH Shafaei, M Saravi, M Sharbat Daran, K Hajian, N Mesbah |
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| Jazyk: | English<br />Persian |
| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 2, Pp 48-54 (2005) |
| Druh dokumentu: | article |
| ISSN: | 1561-4107 2251-7170 |
| Popis: | Background and Objective: Atherosclerosis and its complications are a major cause of ischemic heart diseases. Platelets play an important role in initiation of atherosclerosis and coronary thrombus formation. Large platelets are shown to be hemostatically more active. Evaluation of platelet volume parameters could be useful and significant in prediction and differentiation of coronary events. Methods: In this study, 100 patients with chest pain were divided into 3 groups according to clinical manifestation and standard diagnostic criteria. 25 patients were with unstable angina, 25 patients with chronic stable angina and 50 patients with non-cardiac chest pain as normal population. Platelet indices and count were assayed within 1 to 3 hours, after sampling from venous blood and collection in K3 EDTA, by a Sysmex KX21 analyzer. Data were provided for each group and surveyed by ANOVA and Tukey tests with Pearson correlation and P-value less than 0.05. Findings: Patients with unstable angina had a significant higher MPV (Mean platelet volume) (10.7±0.23 fl), PDW (Platelet distribution width) and PLCR (Platelet-lerge cell ratio) than those in chronic stable angina and normal group (P |
| Databáze: | Directory of Open Access Journals |
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