Acute myeloid leukemia with hepatic infiltration presenting as obstructive jaundice

Autor: Landis R. Walsh, Chaofan Yuan, James T. Boothe, Heather E. Conway, Andres E. Mindiola-Romero, Odeth O. Barrett-Campbell, Swaroopa Yerrabothala, Frederick Lansigan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Leukemia Research Reports, Vol 15, Iss , Pp 100251- (2021)
Druh dokumentu: article
ISSN: 2213-0489
DOI: 10.1016/j.lrr.2021.100251
Popis: We present the case of a 55-year-old woman who presented with laboratory studies concerning for acute myeloid leukemia (AML) as well as obstructive cholestasis. In similar previously reported cases, concerns of chemotherapy toxicity exacerbated by liver dysfunction or concerns of untreated, concurrent cholecystitis in a neutropenic patient often delay initiation of chemotherapy for full medical workup. At admission, our patient was started on the cytoreductive agent hydroxyurea. By day 10 of her medical workup, her liver function had improved with total bilirubin levels normalizing. At that time, full-dose 7 + 3 induction with cytarabine and daunorubicin was then initiated.
Databáze: Directory of Open Access Journals