Periradicular corticosteroid infiltration for radicular pain - comparison of Diprophos and Depomedrone and ozone effects

Autor: David Krahulik, Miroslav Vaverka, Lumir Hrabalek, Daniel Pohlodek, Jakub Jablonsky, Jan Valosek, Jana Zapletalova
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biomedical Papers, Vol 167, Iss 1, Pp 80-84 (2023)
Druh dokumentu: article
ISSN: 1213-8118
1804-7521
DOI: 10.5507/bp.2021.061
Popis: Objectives. To determine the treatment effect of corticosteroids in periradicular therapy (PRT) for radicular pain and to compare different types of corticosteroids and ozone. We also examined the effect in different indication groups for periradicular therapy for each type of treatment agent. Background. Various studies have examined the therapeutic value of periradicular infiltration using treatment agents consisting of local anesthetic and corticosteroids or ozone application for radicular pain. This is the first study to compare different types of corticosteroids and ozone. Methods. Eligible patients with radicular pain who failed conservative management were divided into five indication groups and prospectively followed to assess the PRT effect of corticosteroids or ozone application. PRT was performed under computer tomography (CT) monitoring. A set of three PRT applications in three weeks was applied and the outcome was evaluated using a visual analogue score for back and leg pain. The in-group and between-group treatment effect was tested using the Wilcoxon signed-rank test and the Kruskal-Wallis H-test with Dunn's post-hoc tests, respectively. The dependency between treatment effectiveness and indication for each group was tested using the Kruskal-Wallis H-test and Dunn's post-hoc tests. Results. We prospectively followed 150 patients, randomized into three groups of 50 patients each. The follow-up rate was 100%. All three treatment agents showed a statistically significant treatment effect (P
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