Evaluation of Multimodal Biometric Parameters for Diagnosing Acute Angle Closure Secondary to Lens Subluxation

Autor: Xi Chen, Qinglu Song, Wen Yan, Zijin Wang, Bin Cai, Ying Zhang, Hua Zhong, Qin Chen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Ophthalmology and Therapy, Vol 12, Iss 2, Pp 839-851 (2022)
Druh dokumentu: article
ISSN: 2193-8245
2193-6528
DOI: 10.1007/s40123-022-00638-0
Popis: Abstract Introduction To evaluate the clinical characteristics and multimodal biometric parameters from ultrasound biomicroscopy (UBM) and IOL Master biometry of patients with acute secondary angle-closure due to lens subluxation (ASAC-LS), acute primary angle-closure (APAC), and cataract. Methods This retrospective study included 22 eyes with ASAC-LS, 27 eyes with APAC, and 39 eyes with cataract. Gender, age, affected eye, best corrected visual acuity, axial length, central corneal thickness, and anterior chamber depth (ACD) assessed by UBM and IOL Master were measured and compared between the three groups. In addition, we compared the ratio of ACD (ACD ratio) and the difference of ACD (ACD difference) measured by the two instruments. Logistic regression analysis was conducted to evaluate the predictive factors for lens subluxation. Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cutoff value of biometric parameters to separate ASAC-LS cases from APAC and cataract cases. Results In the ASAC-LS group, the median (interquartile range [IQR]) ACD measured by IOL Master was 2.47 (IQR 1.85–2.92) mm while the median ACD measured by UBM was 3.11 (IQR 2.60–3.76) mm. The difference of ACD measured by the two instruments was statistically significant in the ASAC-LS group (P
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