Prediction of Drug Therapy for Chronic Hepatitis C Depending on the IL28B Gene Polymorphism
| Autor: | Moroz L.V. Moroz L.V., K.Yu. Romanchuk |
|---|---|
| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Aktualʹnaâ Infektologiâ, Vol 2, Iss 3.04, Pp 39-41 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2312-413X 2312-4148 2312-413x 67670628 |
| DOI: | 10.22141/2312-413x.3.04.2014.82437 |
| Popis: | The article analyzed the prognostic significance of IL28b gene polymorphism with regard to the success of antiviral therapy in 152 patients with chronic hepatitis C (63.8 % men and 36.2 % women). Molecular and genetic analysis of IL28V (rs12979860) gene polymorphism, located at a distance of 3 thousand nucleotide pairs from IL28V gene, using the polymerase chain reaction allows to predict the success of combination antiviral therapy, and the presence of C/C genotype can be a predictor of sustained virological response in patients chronic hepatitis C. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|