Transport proteins of parasitic protists and their role in nutrient salvage

Autor: Paul eDean, Peter eMajor, Sirintra eNakjang, Robert eHirt, T Martin eEmbley
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Frontiers in Plant Science, Vol 5 (2014)
Druh dokumentu: article
ISSN: 1664-462X
DOI: 10.3389/fpls.2014.00153
Popis: The loss of key biosynthetic pathways is a common feature of important parasitic protists, making them heavily dependent on scavenging nutrients from their hosts. This is often mediated by specialised transporter proteins that ensure the nutritional requirements of the parasite are met. Over the past decade, the completion of several parasite genome projects has facilitated the identification of parasite transporter proteins. This has been complemented by functional characterisation of individual transporters along with investigations into their importance for parasite survival. In this review, we summarise the current knowledge on transporters from parasitic protists and highlight commonalities and differences in the transporter repertoires of different parasitic species, with particular focus on characterised transporters that act at the host-pathogen interface.
Databáze: Directory of Open Access Journals