| Autor: |
Takashi Tarumi, Takayuki Yamabe, Jun Sugawara |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Artery Research, Vol 25, Iss 1 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1876-4401 |
| DOI: |
10.2991/artres.k.191224.052 |
| Popis: |
Background: Daily assessment of vascular health may predict cardiovascular incidence. Vascular aging index (VAI) calculated from second derivative of photoplethysmogram (SDPTG) is a simple, non-invasive measure possibly reflecting vascular stiffness. However, the effects of daily life events such as mental stress and day-to-day variability as well as its relation to other indices of vascular stiffness remain unclear. Purpose: To determine whether VAI measured by finger SDPTG is 1) correlated with peripheral augmentation index (pAI), 2) altered by acute mental stress, and 3) affected by day-to-day variability. Methods: Simultaneous measurements of finger photoplethysmogram and radial artery tonometry were performed in 68 healthy subjects (age = 22–64 years) of whom 31 subjects were further tested during a 30-second mental arithmetic and 10 subjects underwent day-to-day variability assessment for 5 consecutive days. VAI was calculated from a 20-second segment of photoplethysmogram data [1]. Results: At rest, VAI was positively correlated with pAI (r = 0.62, p < 0.001). During mental arithmetic, VAI increased when compared with the control condition (p = 0.032) whereas pAI did not show significant change. Five day measurements of VAI demonstrated the overall coefficient of variation of 21.1 ± 13.7% across all subjects. Conclusion: VAI calculated from the finger SDPTG is related to a measure of vascular stiffness and sensitive to mental stress with fair day-to-day variability. These findings suggest that VAI assessment needs to be performed at the quiet resting condition. |
| Databáze: |
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| Externí odkaz: |
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