Synthesis and characterisation of biologically compatible TiO2 nanoparticles

Autor: Smith Tim, Cheyne Richard, Trembleau Laurent, Mclaughlin Abbie
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Nanoscale Research Letters, Vol 6, Iss 1, p 423 (2011)
Druh dokumentu: article
ISSN: 1931-7573
1556-276X
Popis: Abstract We describe for the first time the synthesis of biocompatible TiO2 nanoparticles containing a functional NH2 group which are easily dispersible in water. The synthesis of water dispersible TiO2 nanoparticles coated with mercaptosuccinic acid is also reported. We show that it is possible to exchange the stearic acid from pre-synthesised fatty acid-coated anatase 5-nm nanoparticles with a range of organic ligands with no change in the size or morphology. With further organic functionalisation, these nanoparticles could be used for medical imaging or to carry cytotoxic radionuclides for radioimmunotherapy where ultrasmall nanoparticles will be essential for rapid renal clearance.
Databáze: Directory of Open Access Journals
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