Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?

Autor: Isabella Piva, Giuseppe Lo Monte, Angela Graziano, Roberto Marci
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 8, Iss 11, Pp OD01-OD02 (2014)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2014/8727.5103
Popis: Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period.
Databáze: Directory of Open Access Journals