The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness

Autor: Kerem Doğa Seçkin, Mehmet Fatih Karslı, Burak Yücel, Elif Akkaş Yılmaz, Murat Öz, Deniz Balsak, Hüseyin Kıyak, Gökhan Yıldırım
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Gynecology Obstetrics & Reproductive Medicine, Vol 22, Iss 1 (2016)
Druh dokumentu: article
ISSN: 1300-4751
DOI: 10.21613/GORM.2016.108
Popis: OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding. STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups. RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p>0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p
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