Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood
| Autor: | Jieun Kim, Hyebin Koh, Xing Zhen, Dong-Seok Lee, Hye-Yeong Ha, Jong-Hee Lee |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Stem Cell Research, Vol 51, Iss , Pp 102199- (2021) |
| Druh dokumentu: | article |
| ISSN: | 1873-5061 62945009 |
| DOI: | 10.1016/j.scr.2021.102199 |
| Popis: | Human induced pluripotent stem cells with indefinite propagation in vitro provide a potential donor source of cells including erythroid cells for human therapy. Since group O D-negative (RhD−) blood cells are considered as universal donors for transfusion, it is compelling to derive iPSC line from group O/RhD− sample as a new cellular source to generate universal RBCs. The resulting iPSC line derived from group O/RhD− somatic source showed typical features of pluripotent stem cells and could provide an unprecedented cellular tool to develop universal therapeutics for blood transfusion. |
| Databáze: | Directory of Open Access Journals |
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