Comparison of Clinico-Pathological Features Between Epithelial Ovarian Cancer Patients With and Without Endometriosis: A Cross-Sectional Study

Autor: Mehri Jafari Shobeiri, Navideh Hajagaei Saeidi, Heidar Ali Esmaeili, Ali Dastranj Tabrizi, Yasmin Pouraliakbar, Parvin Mostafa-Gharabaghi, Manizheh Sayyah-Melli, Maryam Vaezi, Vahideh Rahmani, Sajjad Pourasghari
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Crescent Journal of Medical and Biological Sciences, Vol 11, Iss 1, Pp 38-42 (2024)
Druh dokumentu: article
ISSN: 2148-9696
DOI: 10.34172/cjmb.2023.31
Popis: Objectives: Women with endometriosis have a high risk of developing ovarian carcinoma that may occur due to endometriosis lesions. There is few research have so far focused on the clinical factors in patients with endometriosis-associated ovarian cancer (EAOC). Accordingly, this study aimed at comparing the demographic and obstetric characteristics between ovarian cancer with and without endometriosis Materials and Methods: This cross-sectional study was conducted on 20 EAOC patients and 140 non-EAOC individuals who had gone under surgery from 2011-17 at Al-Zahra hospital. Clinico-pathological characteristics of the two groups including first group only had malignant epithelial ovarian tumor (non-EAOC) and second group had both malignant epithelial ovarian tumor and endometriosis (EAOC). P value less than 0.05 was considered statistically significant. Results: EAOC cases were significantly younger (P=0.002) and had lower number of pregnancy (P=0.002), parity (P=0.004), and term pregnancy (P=0.005) than non-EAOC patients. A large proportion of EAOC cases had clear cell and endometrioid histopathology in comparison to non-EAOC individuals (P
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