| Autor: |
Yue Xu, Hua Li, Lixue Fan, Yisha Chen, Li Li, Xiaojing Zhou, Ruixi Li, Yuru Cheng, Haiyan Chen, Zhenwei Yuan |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of Advanced Research, Vol 28, Iss , Pp 165-174 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2090-1232 |
| DOI: |
10.1016/j.jare.2020.08.003 |
| Popis: |
Introduction: Photothermal therapy (PTT) was considered as one of the most promising cancer therapies to overcome the severe side effects caused by chemotherapy. Objective: To develope four thiophene analogs to construct novel organic photothermal agents (PTAs) for many biomedical applications in cancer biosensing and photothermal therapies. Methods: The efficacy of four compounds was demonstrated by studies of photothermal properties as well as photothermal therapeutic effects. Results: Tumor ablation experiments indicated that HTN2 can effectively suppress tumors in vivo and in vitro as a novel PTA. Conclusion: PTAs that we designed and synthesized with their advantage of good biocompatibility and facile structural design could be candidates for PTT. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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