Low serum vitamin D concentration is correlated with anemia, microinflammation, and oxidative stress in patients with peritoneal dialysis

Autor: Chi Zhang, Junsheng Wang, Xiaohui Xie, Dong Sun
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1479-5876
DOI: 10.1186/s12967-021-03077-w
Popis: Abstract Background Peritoneal dialysis (PD) is a form of dialysis to replace the function of kidney, that uses the peritoneum as a dialysis membrane to remove metabolites and water retained in the body. Vitamin D deficiency is prevalent in patients treated with PD. This research investigated the correlation between serum 25-hydroxyvitamin D [25(OH)D] concentration and anemia, microinflammation, and oxidative stress in PD patients. Methods 62 PD patients and 56 healthy volunteers were recruited in this research. Serum concentrations of 25(OH)D and basic parameters of anemia were detected. The correlation between serum 25(OH)D concentration with anemia, oxidative stress, and microinflammatory state were analyzed. Results In the PD group, the concentration of 25(OH)D was lower than the healthy control (HC) group (p
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