Autor: |
Dorothea L. Floris, José O. A. Filho, Meng-Chuan Lai, Steve Giavasis, Marianne Oldehinkel, Maarten Mennes, Tony Charman, Julian Tillmann, Guillaume Dumas, Christine Ecker, Flavio Dell’Acqua, Tobias Banaschewski, Carolin Moessnang, Simon Baron-Cohen, Sarah Durston, Eva Loth, Declan G. M. Murphy, Jan K. Buitelaar, Christian F. Beckmann, Michael P. Milham, Adriana Di Martino |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
|
Zdroj: |
Molecular Autism, Vol 12, Iss 1, Pp 1-17 (2021) |
Druh dokumentu: |
article |
ISSN: |
2040-2392 |
DOI: |
10.1186/s13229-021-00415-z |
Popis: |
Abstract Background Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have, however, been challenged by the limited availability of female data. Methods We addressed this gap by using a large sample of males and females with autism and neurotypical (NT) control individuals (ABIDE; Autism: 362 males, 82 females; NT: 409 males, 166 females; 7–18 years). Discovery analyses examined main effects of diagnosis, sex and their interaction across five resting-state fMRI (R-fMRI) metrics (voxel-level Z > 3.1, cluster-level P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|