Seroprevalence and Potential Risk Factors of Hepatitis E Virus among Pregnant Women in Khartoum, Sudan

Autor: Alaa Abdulrahman Mohammad Mustafa, Wafaa Mohammed Abdalla, Hind Haidar Ahmed, Samar M. Saeed, Ahmed Ibrahim Hashim, Sarrah Elnoor Khalifa, Ahmed Bakheet AbdAlla, Tagwa Salah Ahmed, Kashaf Junaid
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Pure and Applied Microbiology, Vol 16, Iss 1, Pp 585-592 (2022)
Druh dokumentu: article
ISSN: 0973-7510
2581-690X
DOI: 10.22207/JPAM.16.1.57
Popis: Although hepatitis E virus (HEV) infection has been widely understood as a public health concern in pregnant females, it is sometimes overlooked because of unusual observations of hepatitis E-induced complications during pregnancy. The objective of this descriptive cross-sectional study was to find out how frequent Hepatitis E virus infection is in pregnant women in Sudan. Blood samples were collected from pregnant women (n = 90) attending Khartoum North Hospital from February to December 2019. The specimens were investigated for Hepatitis E virus IgG and IgM antibodies using the commercial kits based on the enzyme immunosorbent assay (ELISA) technique. Out of ninety pregnant women, 36 (40%) were found positive for IgG antibodies, and 5 (6%) were tested positive for IgM antibodies. In addition, 13 (14.5%) of the positive cases are women in their third trimester. These data showed a significant association between previous Hepatitis E virus infection and miscarriage (p
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