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Chang Jiang,1–3,* Wan-Ming Hu,2–4,* Fang-Xin Liao,1–3 Qiong Yang,1–3 Ping Chen,1–3 Yu-Ming Rong,1–3 Gui-Fang Guo,1–3 Chen-Xi Yin,2,3,5 Bei Zhang,1–3 Wen-Zhuo He,1–3 Liang-Ping Xia1–3 1VIP Department, Sun Yat-sen University Cancer Center, 2State Key Laboratory of Oncology in South China, 3Collaborative Innovation Center for Cancer Medicine, 4Department of Pathology, 5Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People’s Republic of China *These authors contributed equally to this work Purpose: To investigate the prognostic relevance of preoperative peripheral neutrophil-to-lymphocyte ratio (NLR) in gastrointestinal stromal tumor (GIST) patients.Materials and methods: We enrolled 129 consecutive GIST patients who underwent initial curative surgical resection with or without adjuvant/palliative imatinib treatment in our study. Blood NLR was calculated as neutrophil count (number of neutrophils ×109/L) divided by lymphocyte count (number of lymphocytes ×109/L). Survival curves were constructed by using the Kaplan–Meier method. Univariate and multivariate Cox proportional hazard regression models were performed to identify associations with outcome variable. All tests were two-sided, and P |
