Mixed methods feasibility study for the surviving opioid overdose with naloxone education and resuscitation (SOONER) trial

Autor: Aaron M. Orkin, Mercy Charles, Kristine Norris, Rekha Thomas, Leigh Chapman, Amy Wright, Douglas M. Campbell, Curtis Handford, Michelle Klaiman, Shaun Hopkins, Rita Shahin, Kevin Thorpe, Peter Jüni, Janet Parsons, Kate Sellen, Nick Goso, Richard Hunt, Pamela Leece, Laurie J. Morrison, Vicky Stergiopoulos, Suzanne Turner, Carol Strike
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Resuscitation Plus, Vol 6, Iss , Pp 100131- (2021)
Druh dokumentu: article
ISSN: 2666-5204
DOI: 10.1016/j.resplu.2021.100131
Popis: Aim: We plan to conduct a randomised clinical trial among people likely to witness opioid overdose to compare the educational effectiveness of point-of-care naloxone distribution with best-available care, by observing participants’ resuscitation skills in a simulated overdose. This mixed methods feasibility study aims to assess the effectiveness of recruitment and retention strategies and acceptability of study procedures. Methods: We implemented candidate-driven recruitment strategies with verbal consent and destigmatizing study materials in a family practice, emergency department, and addictions service. People ≥16 years of age who are likely to witness overdose were randomized to point-of-care naloxone distribution or referral to an existing program. We evaluated participant skills as a responder to a simulated overdose 3–14 days post-recruitment. Retention strategies included flexible scheduling, reminders, cash compensation and refreshments. The primary outcome was recruitment and retention feasibility, defined as the ability to recruit 28 eligible participants in 28 days, with
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