Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

Autor: Eduardo A.A. Pinheiro, Josiwander M. Carvalho, Diellem C.P. dos Santos, Andre O. Feitosa, Patricia S.B. Marinho, Giselle Maria S.P. Guilhon, Lourivaldo S. Santos, Afonso L.D. de Souza, Andrey M.R. Marinho
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Anais da Academia Brasileira de Ciências, Vol 85, Iss 4, Pp 1247-1253 (2013)
Druh dokumentu: article
ISSN: 1678-2690
0001-3765
DOI: 10.1590/0001-3765201395512
Popis: The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.
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