Hypofibrinogenemia following injury in 186 children and adolescents: identification of the phenotype, current outcomes, and potential for intervention

Autor: Charles E Wade, Bryan A Cotton, David E Meyer, Charles Cox, Jessica Cardenas, Jan-Michael Van Gent, Justin Gerard, Christian Gage
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Druh dokumentu: article
ISSN: 2397-5776
DOI: 10.1136/tsaco-2023-001108
Popis: Objectives Recent studies evaluating fibrinogen replacement in trauma, along with newly available fibrinogen-based products, has led to an increase in debate on where products such as cryoprecipitate belong in our resuscitation strategies. We set out to define the phenotype and outcomes of those with hypofibrinogenemia and evaluate whether fibrinogen replacement should have a role in the initial administration of massive transfusion.Methods All patients
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