LncRNA SNHG15 contributes to doxorubicin resistance of osteosarcoma cells through targeting the miR-381-3p/GFRA1 axis

Autor: Zhang Jinshan, Rao Dan, Ma Haibo, Kong Defeng, Xu Xiaoming, Lu Hougen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Open Life Sciences, Vol 15, Iss 1, Pp 871-883 (2020)
Druh dokumentu: article
ISSN: 2391-5412
DOI: 10.1515/biol-2020-0086
Popis: Osteosarcoma is a common primary malignant bone cancer. Long noncoding RNA small nucleolar RNA host gene 15 (SNHG15) has been reported to play an oncogenic role in many cancers. Nevertheless, the role of SNHG15 in the doxorubicin (DXR) resistance of osteosarcoma cells has not been fully addressed.
Databáze: Directory of Open Access Journals