Major depressive disorder as a risk factor for suicidal ideation for attendees of educational institutions: a meta-analysis and meta-regression

Autor: Laura Costa Souza, Lucas Pequeno Galvão, Henrique Soares Paiva, Cintia de Azevedo-Marques Périco, Antonio Ventriglio, Julio Torales, João Maurício Castaldelli-Maia, Anderson Sousa Martins-da-Silva
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2023
Předmět:
Zdroj: Revista Paulista de Pediatria, Vol 41 (2023)
Druh dokumentu: article
ISSN: 1984-0462
DOI: 10.1590/1984-0462/2023/41/2021344
Popis: Abstract Objective: This study aimed to analyze the effect of major depressive disorder (MDD) as a risk factor for suicidal ideation in individuals whose ages varied from 11 to 24 years and who were attending educational institutions. Data source: A systematic review was carried out by searching in PubMed and Biblioteca Virtual em Saúde (BVS). Original studies conducted in educational institutions, including individuals whose age varied from 11 to 24 years, in English, Spanish, or Portuguese were included. Data synthesis: Eight studies were selected for the meta-analysis, including 35,443 youths, with an average age of 16.8 years, predominantly female (51.2%), and from middle-income Asian countries (91.6%). An odds ratio of MDD of 3.89 (95%CI 2.46–6.17) for suicide ideation in youth was found. Subgroup analysis showed higher effects in Asia (OR=4.71; 95%CI 3.22–6.89) than Americas (OR=1.71; 95%CI 1.44–2.03). The meta-regression model indicated that younger adolescents (coef=-0.63; 95%CI 1.09–-0.18; p
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