A case report of a drug‐induced liver injury (DILI) caused by multiple antidepressants with causality established by the updated Roussel Uclaf causality assessment method (RUCAM) and in vitro testing

Autor:	Miguel González‐Muñoz, Jaime Monserrat Villatoro, Eva Marín‐Serrano, Stefan Stewart, Belén Bardón Rivera, Jesús Marín, Lucía Martínez de Soto, Enrique Seco Meseguer, Elena Ramírez
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	antidepressants causality assessment drug‐induced liver injury (DILI) lymphocyte transformation test (LTT) pharmacovigilance Roussel Uclaf Causality Assessment Method (RUCAM) Medicine Medicine (General) R5-920
Zdroj:	Clinical Case Reports, Vol 8, Iss 12, Pp 3104-3108 (2020)
Druh dokumentu:	article
ISSN:	2050-0904
DOI:	10.1002/ccr3.3348
Popis:	Abstract A 56‐year‐old female patient was hospitalized because of a lack of response and poor tolerance to multiple antidepressants, which included an episode of DILI. During hospitalization, the patient suffered another episode of DILI. Causality was assessed both by RUCAM and Lymphocyte Transformation Test, allowing to identify a safer medication.
Databáze:	Directory of Open Access Journals
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