Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Autor: Alexander Bartelt, Clara John, Nicola Schaltenberg, Jimmy F. P. Berbée, Anna Worthmann, M. Lisa Cherradi, Christian Schlein, Julia Piepenburg, Mariëtte R. Boon, Franz Rinninger, Markus Heine, Klaus Toedter, Andreas Niemeier, Stefan K. Nilsson, Markus Fischer, Sander L. Wijers, Wouter van Marken Lichtenbelt, Ludger Scheja, Patrick C. N. Rensen, Joerg Heeren
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15010
Popis: Activation of brown adipose tissue (BAT) reduces the development of atherosclerosis in animal models. Here the authors show that BAT activation also increases reverse cholesterol transport and turnover of high-density lipoprotein, which likely contributes to the anti-atherosclerotic effect of BAT activation.
Databáze: Directory of Open Access Journals