GROWTH PARTICULARS OF PITUITARY MACROADENOMAS WITH VARIOUS HORMONAL ACTIVITIES
| Autor: | I. A. Ilovayskaya, A. V. Dreval', Yu. G. Krivosheeva, L. I. Astaf'eva, G. A. Stashuk |
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| Jazyk: | ruština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Alʹmanah Kliničeskoj Mediciny, Vol 44, Iss 4, Pp 451-456 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2072-0505 2587-9294 |
| DOI: | 10.18786/2072-0505-2016-44-4-451-456 |
| Popis: | Background: Pituitary adenoma is not as infrequent as thought previously. The prevalence of macroadenomas in general population is up to 0.16–0.2%. Magnetic resonance imaging (MRI) is a method of choice in diagnosis of pituitary adenomas. Until now, specifics of imaging of pituitary adenomas with various hormonal activities have not been discussed.Aim: To analyze comparatively the size, volumes and growth direction in pituitary macroadenomas with various hormonal activities.Materials and methods: We analyzed MRI images of 305 patients with hypophyseal adenomas of more than 10 mm diameter, among them with non-functioning adenomas (n=109), prolactinomas (n=58), and somatotropinomas (n=138).Results: Depending on their hormonal activity, hypophyseal adenomas had different volumes (р0.05). Non-functioning hypophyseal adenomas and prolactinomas demonstrated mostly suprasellar growth (in 83.5 and 79.3% of cases, respectively), whereas somatotropinomas were growing mostly in infrasellar direction (66.1%).Conclusion: These characteristic features of hypophyseal macroadenomas with various hormonal activities could be used for differential diagnosis, which may help to optimize patient assessment during the diagnostic work-up. |
| Databáze: | Directory of Open Access Journals |
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