Surgical site infection after laparoscopic resection of colorectal cancer is associated with compromised long-term oncological outcome

Autor: Nana Sugamata, Takashi Okuyama, Emiko Takeshita, Haruka Oi, Yuhei Hakozaki, Shunya Miyazaki, Musashi Takada, Takashi Mitsui, Takuji Noro, Hideyuki Yoshitomi, Masatoshi Oya
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-022-02578-2
Popis: Abstract Background We evaluated the influence of infectious complications, particularly surgical site infection (SSI), on long-term oncological results after elective laparoscopic resection of colorectal cancer. Methods A total of 199 patients who underwent laparoscopic elective resection with negative resection margins for stage I–III colorectal cancer were retrospectively examined. The postoperative course was recorded based on hospital records, and cancer relapse was diagnosed based on radiological or pathological findings under a standardized follow-up program. The severity of complications was graded using Clavien-Dindo (CD) classification. Results SSI was found in 25 patients (12.6%), with 12 (6.0%) showing anastomotic leak. The postoperative relapse-free survival (RFS) rate was significantly lower in patients with SSI (49.2%) than in patients without SSI (87.2%, P
Databáze: Directory of Open Access Journals
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