Autor: |
Mustafa Aydın, Işılay Özeren, Ayşen Orman, Samet Benli, Nilay Hakan, Erdal Taşkın |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
|
Zdroj: |
Journal of Behçet Uz Children's Hospital, Vol 14, Iss 1, Pp 56-64 (2024) |
Druh dokumentu: |
article |
ISSN: |
2822-4469 |
DOI: |
10.4274/jbuch.galenos.2024.34032 |
Popis: |
Objective: Neonatal sepsis is an important cause of neonatal mortality and morbidity, especially in low birth-weight premature babies. This study aimed to examine the clinical and laboratory features of cases with culture-positive neonatal sepsis. Method: Medical records of 233 newborn infants with culture-positive sepsis among 4241 hospitalized patients between January 2013 and December 2017 were reviewed. Demographic and clinical data of these patients were retrospectively recorded. Results: The majority of patients was extremely and moderately preterm infants (39.1% vs. 11.6%). These patients had a history of invasive mechanical ventilation (74.2%) or central catheterization (26.9%). The mostly isolated pathogens (56.2%) were Gram-negative bacteria, especially Klebsiella pneumoniae in 67 (28.8%) cases. Post-hoc test showed a statistically significant difference in the incidence rates of leukopenia between patients infected with Gram-positive, Gram-negative bacteria and fungi (12.3%, 16.8% and 17.2%, respectively) (p=0.021). Patients who developed leukopenia (n=36, 15.5%) had a higher mortality rate compared to those with leukocytosis (n=50, 21.5%) (72.2% vs. 50%, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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