Clozapine Can Be the Good Option in Resistant Mania

Autor: S. M. Yasir Arafat, S. M. Atikur Rahman, Md. Maruful Haque, Mohsin Ali Shah, Sultana Algin, Jhunu Shamsun Nahar
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Case Reports in Psychiatry, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-682X
2090-6838
DOI: 10.1155/2016/3081704
Popis: Bipolar mood disorder is a mental disorder with a lifetime prevalence rate of about 1% in the general population and there are still a proportion of individuals who suffer from bipolar mood disorders that are resistant to standard treatment. Reporting clozapine responsive mania that was not responding to two previous consecutive atypical antipsychotics and one typical antipsychotic was aimed at. A 17-year-old male manic patient was admitted into the psychiatry inpatient department and was nonresponsive to Risperidone 12 mg daily for 4 weeks, Olanzapine 30 mg daily for 3 weeks, and Haloperidol 30 mg daily for 3 weeks, along with valproate preparation 1500 mg daily. He was started on clozapine as he was nonresponsive to Lithium in previous episodes and did not consent to starting Electroconvulsive Therapy (ECT). He responded adequately to 100 mg clozapine and 1500 mg valproate preparation and remission happened within 2 weeks of starting clozapine. Clozapine can be a good option for resistant mania and further RCT based evidences will strengthen the options in treating resistant mania.
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