Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus

Autor: F. O. Ushanova, T. Y. Demidova, T. N. Korotkova
Jazyk: English<br />Russian
Rok vydání: 2023
Předmět:
Zdroj: Сахарный диабет, Vol 26, Iss 6, Pp 526-536 (2023)
Druh dokumentu: article
ISSN: 2072-0351
2072-0378
DOI: 10.14341/DM13049
Popis: Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus© Fatima O. Ushanova1*, Tatiana Y. Demidova1, Tatiana N. Korotkova21Pirogov Russian National Research Medical University, Moscow, Russia2Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, RussiaBACKGROUND: The prevalence of gestational diabetes mellitus (GDM) is growing rapidly, along with which the typical portrait of a pregnant woman with this disease is changing. Frequent detection of GDM in the early stages of pregnancy causes a high interest in the study of new mechanisms of its development.AIM: Evaluation of the state of the incretin response based on the analysis of the secretion of GLP-1, glucagon, insulin and c-peptide in pregnant women with different periods of GDM development.MATERIALS AND METHODS: A single-center prospective comparative uncontrolled study that included pregnant women with GSD, divided into 2 groups depending on the duration of the disease: group 1 — pregnant women who were diagnosed at
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