Levels of Serum Calcium and Magnesium in Pre-eclamptic and Normal Pregnancy: A Study from Coastal India

Autor: Deepa V Kanagal, Aparna Rajesh, Kavyarashmi Rao, Ullal Harshini Devi, Harish Shetty, Sucheta Kumari, Prasanna Kumar Shetty
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 8, Iss 7, Pp OC01-OC04 (2014)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2014/8872.4537
Popis: Background: Pre-eclampsia is one of the major causes of maternal and fetal morbidity and mortality. Though the aetiology is obscure, recent studies indicate that serum levels of calcium and magnesium may have a role in pre-eclampsia. Aim: The aim of this study was to find out the relationship of serum levels of calcium and magnesium in pre-eclamptic pregnancies compared to normal pregnancies in women from southern coastal India. Settings and Design: This study was done in a medical college hospital in southern coastal India. Materials and Methods: The blood samples from 60 preeclamptic women and an equal number of controls were analysed for calcium and magnesium levels. Data on Body Mass Index, maternal and gestational ages, serum calcium and magnesium were compared between the two groups. Outcome of pregnancy was analysed in both the groups and compared. Statistical Analysis: Data was expressed as Mean ± Standard Deviation. Data analysis was done by SPSS version 20. Comparison of serum levels of the elements between the two groups was performed by Independent t-test and Chi-square test and P-value of < 0.05 was considered as statistically significant. Results: The serum calcium concentration was significantly lower in the pre-eclamptic group compared to normotensives (7.84 ± 0.87 mg/dl Vs 8.97± 0.69 mg/dl, p
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