| Autor: |
Elizabeth Torres-Anguiano, Itzel Sánchez-López, Angeles Garduno-Robles, Jorge David Rivas-Carrillo, Edgar Alfonso Rivera-León, Sergio Sánchez-Enríquez, Luis Fernando Ornelas-Hernández, Fernando Zazueta León-Quintero, Eduardo Narciso Salazar León-Quintero, Guillermo Enrique Juárez-López, Fernando Antonio Sánchez-Zubieta, Mariana Ochoa-Bru, Abraham Zepeda-Moreno |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Infectious Disease Modelling, Vol 8, Iss 2, Pp 445-457 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2468-0427 |
| DOI: |
10.1016/j.idm.2023.04.004 |
| Popis: |
Objectives: To determine whether air pollution or changes in SARS-CoV-2 lineages lead to an increase in mortality. Methods: Descriptive statistics were used to calculate rates of infection (2020–2021). RT–PCR was used to compare viral loads from October 2020 to February 2021. Next-generation sequencing (NGS) (n = 92) was used to examine and phylogenetically map SARS-CoV-2 lineages. A correlative “air pollution/temperature” index (I) was developed using regression analysis. PM2.5, PM10, O3, NO2, SO2, and CO concentrations were analyzed and compared to the mortality. Results: The mortality rate during the last year was ∼32%. Relative SARS-CoV-2 viral loads increased in December 2020 and January 2021. NGS revealed that approximately 80% of SARS-CoV-2 linages were B.1.243 (33.7%), B1.1.222 (11.2%), B.1.1 (9%), B.1 (7%), B.1.1.159 (7%), and B.1.2 (7%). Two periods were analyzed, the prehigh- and high-mortality periods and no significant lineage differences or new lineages were found. Positive correlations of air pollution/temperature index values with mortality were found for IPM2.5 and IPM10. INO2. ISO2, and ICO but not for O3. Using ICO, we developed a model to predict mortality with an estimated variation of ∼±5 deaths per day. Conclusion: The mortality rate in the MZG was highly correlated with air pollution indices and not with SARS-CoV-2 lineage. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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