Brain hypoxia and metabolic crisis are common in patients with acute brain injury despite a normal intracranial pressure

Autor:	Anton Lund, Anna Forsberg Madsen, Tenna Capion, Helene Ravnholt Jensen, Axel Forsse, John Hauerberg, Sigurður Þor Sigurðsson, Tiit Illimar Mathiesen, Kirsten Møller, Markus Harboe Olsen
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Brain hypoxia Energy Metabolism Microdialysis Intracranial pressure Intracranial hypertension Oxygen Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-75129-2
Popis:	Abstract Patients with acute brain injury are vulnerable to secondary deterioration, which may go undetected by traditional monitoring. However, multimodal neuromonitoring of brain tissue oxygen tension (PbtO2) and energy metabolism may be able to detect such episodes. We report a retrospective, observational study of 94 patients with aneurysmal subarachnoid haemorrhage (SAH) or traumatic brain injury (TBI) who underwent multimodal neuromonitoring during admission. We examined the co-occurrence of pathological neuromonitoring values: elevated intracranial pressure (ICP, > 20 mmHg), inadequate cerebral perfusion pressure (CPP, 40 and a glucose level
Databáze:	Directory of Open Access Journals
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